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Prevention of disease induced by a partially heterologous AIDS virus in Rhesus monkeys by using an adjuvanted multicomponent protein vaccine Voss G, et al. Journal of Virology January 2003, p. 1049-1058, Vol. 77, No. 2 Link In this report they demonstrate that a multiantigen subunit protein vaccine was able to prevent the development of disease induced in rhesus monkeys by a partially heterologous AIDS virus. The combination of the regulatory proteins Nef and Tat together with the structural protein gp120 was required for vaccine efficacy. (vaccines)
—Posted: January 6, 2003
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