Evolution of the cutaneous immune response to experimental Haemophilus ducreyi infection and its relevance to HIV-1 acquisition
Humphreys TL, et al.Haemophilus ducreyi causes the sexually transmitted disease chancroid, which facilitates HIV-1 transmission. Together with the disruption of mucosal and skin barriers, the presence of cells with up-regulated HIV-1 coreceptors in H. ducreyi-infected lesions may provide an environment that facilitates the acquisition of R5 (CCR5), X4 (CXCR4), and dual-tropic HIV-1 strains.
Journal of Immunology
169 (11): 6316-6323 DEC 1 2002
—Posted: December 30, 2002
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