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Capture and transfer of simian immunodeficiency virus by macaque dendritic cells is enhanced by DC-SIGN Monica T. Yu Kimata et al.
Journal of Virology
December 2002, p. 11827-11836, Vol. 76, No. 23
Link These data demonstrate that pig-tailed macaque dendritic cells (DC)-specific ICAM-3-grabbing nonintegrin (DC-SIGN) plays a central role in transmitting virus from macaque DCs to T cells, and they suggest that SIVmne variants may differ in their interactions with ptDC-SIGN. Thus, SIVmne infection of pig-tailed macaques may provide an opportunity to investigate the significance of DC-SIGN in primate lentiviral infections.
—Posted: November 12, 2002
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