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Review: Breast milk and HIV-1: vector of transmission or vehicle of protection? Kourtis AP, et al.
The Lancet Infectious Diseases
3(12), 1 December 2003
Link Mechanisms associated with transmission of HIV-1 through breastfeeding and factors related to protection from such transmission remain poorly understood. In this review, they focus on the cellular origin of HIV in breast milk and on immune factors within the milk that may offer protection from transmission of HIV infection. The presence of innate immunity and induction of adaptive immunity against HIV is explored: in particular, specific antibodies, cellular responses, and their significance. The role of mucosal immune activation and epithelial integrity in HIV transmission is also addressed.
—Posted: December 8, 2003
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