Human immunodeficiency virus-induced apoptosis of human hepatocytes via CXCR4
Vlahakis SR, et al.HIV infection is commonly associated with liver dysfunction. Here, they investigated whether hepatocyte death could result from the HIV env signaling through CXCR4 on the hepatocyte, and found that HIV can directly cause hepatocyte death in humans by signaling through CXCR4, without infecting the cell.
Journal of Infectious Diseases
2003 Nov 15;188(10):1455-60
—Posted: December 4, 2003
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