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Review: Macrophages and lymphocytes differentially modulate the ability of RANTES to inhibit HIV-1 infection Schmidtmayerova H, et al. Journal of Leukocyte Biology 2003;74:781-790 Link Results demonstrate dichotomous effects of RANTES on HIV-1 entry at the moment of infection, and on production and spread of virus progeny in primary macrophages. Since macrophages serve as a reservoir of HIV-1, this may contribute to the failure of endogenous chemokines to successfully eradicate the virus.
—Posted: December 2, 2003
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