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Review: Regulation of HIV-1 gene transcription: from lymphocytes to microglial cells Schaeffer E, et al.
Journal of Leukocyte Biology
2003;74:736-749
Link Review of the multiple cell type-specific interplays between cellular and viral factors crucial for the virus to leave latency and actively replicate in a great diversity of cells, despite the variability of its long terminal repeat region in different HIV strains. Knowledge about the molecular mechanisms underlying transcriptional regulatory events helps in the search for therapeutic agents that target the step of transcription in anti-HIV strategies.
—Posted: December 2, 2003
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