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Review: The role of dendritic cell C-type lectin receptors in HIV pathogenesis Cunningham AL, et al.
Journal of Leukocyte Biology
2003;74:710-718
Link The mechanism of binding, internalization, infection and transfer of HIV to CD4 lymphocytes is of great interest. Recently, the role of the C-type lectin DC-SIGN as a dendritic cell receptor for HIV has been intensively studied with in vitro monocyte-derived dendritic cells. However, it is clear that other C-type lectin receptors such as Langerin on Langerhan cells and mannose receptor on dermal dendritic cells are at least equally important for gp120 binding on epithelial dendritic cells.
—Posted: December 2, 2003
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