Review: The role of dendritic cell C-type lectin receptors in HIV pathogenesis
Cunningham AL, et al.The mechanism of binding, internalization, infection and transfer of HIV to CD4 lymphocytes is of great interest. Recently, the role of the C-type lectin DC-SIGN as a dendritic cell receptor for HIV has been intensively studied with in vitro monocyte-derived dendritic cells. However, it is clear that other C-type lectin receptors such as Langerin on Langerhan cells and mannose receptor on dermal dendritic cells are at least equally important for gp120 binding on epithelial dendritic cells.
Journal of Leukocyte Biology
—Posted: December 2, 2003
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