|
In vivo kinetics and biodistribution of a HIV-1 DNA vaccine after administration in mice Kim WB, et al.
Archives of Pharmacal Research
26 (6): 493-498 JUN 2003
Link In this study we have investigated the pharmacokinetics and tissue distribution of GX-12, a multiple plasmid DNA vaccine for the treatment of HIV-1 infection. The rapid in vivo degradation of GX-12 and absence of persistence in non-target tissues suggest that the risk of potential gene-related toxicities by GX-12 administration, such as expression in non-target tissues, insertional mutagenesis and germline transmission, is minimal. (vaccines)
—Posted: July 29, 2003
More journal headlines: This month | Last month | Search archive
|
