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May 19, 2013
 
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Vol. 3, No. 11, 13 June 2003
Other Issues:



AIDScience Perspectives:
Predicting the public health impact of antiretrovirals: preventing HIV in developing countries
The recent U.S. government $15 billion pledged for AIDS in Africa and the Caribbean has opened a debate regarding what proportion of this sum should be allocated to prevention versus treatment. Researchers from UCLA and Harvard Medical School argue, with caution, that antiretrovirals should be considered as a prevention tool and not simply as a therapeutic tool.

— By Sally M. Blower and Paul Farmer 
[About AIDScience articles] [See recent AIDScience articles]
 
Hot News:
Monocyte protein profiles may predict HIV-1–associated dementia (HAD)
Certain protein patterns in blood cells may be a sign an HIV-infected patient is at risk of dementia. The study supports the hypothesis that changes in monocyte function parallel the development of HAD. Neurology 60, 1931 (2003).
 
How many HIV preventive vaccine trials are underway?
The International AIDS Vaccine Initiative (IAVI) has introduced a new feature, "Clinical Trials Watch," which will track ongoing clinical testing of HIV vaccines. Download a PDF of the document with details on types of vaccines, sponsors/manufacturers, sites, etc., updated 16 June 2003.
 
HIV testing — United States, 2001
To characterize the prevalence of HIV-antibody testing among U.S. adults, CDC analyzed data from the 2001 Behavioral Risk Factor Surveillance System (BRFSS). The findings document variability in HIV testing prevalence by area and by sex within areas, underscoring the ongoing need to promote voluntary HIV counseling and testing. MMWR 52(23), 540, 13 June, 2003.
 
Latest News Headlines
[What is this?]
Origin of AIDS traced back another step, researchers say
Immune Response Corp. initiates treatment interruption study in Spain
Caribbean leaders irked on AIDS funding
CDC: Half of U.S. adults have been tested for HIV
Indian leaders accused of downplaying HIV
Latin American nations win price cuts on HIV drugs
Killer pricing
Powell: AIDS may hurt developing nations
International businesses praised, prodded on AIDS
Medarex begins phase I trial of MDX-010 antibody
Africa AIDS conference to be held in Nairobi in September
Targeted Genetics presents preclinical results from AIDS vaccine
Needle exchange programs do not cause an increase in injection drug use
Ugandan's key to White House: AIDS
Study shows HIV drugs restore cholesterol levels
More treatable AIDS-related lymphomas
AIDS begins to widen its reach in India
Study targets AIDS therapy
VaxGen awarded SBIR grant to identify novel antigens for possible new HIV vaccines
Keeping an AIDS promise (editorial)
Small company moving beyond the battle to cure AIDS
In post-9/11 world, vaccine research gains new respect
U.K.: Universities venture gives MMI a boost
Dirty Needles Misjudged in AIDS in Africa
Study: Failure to curb HIV will cost U.S. billions
Warning for drugs giants on tackling third world risks
AIDS Spreading rapidly in Russia
AIDS in South Florida: The virus is on a rampage in our back yard
China issues directive on treating AIDS patients with SARS
Targeted Genetics stock jumps on HIV data
Forsaking health to join the HIV club
Global Fund for AIDS, Tuberculosis, Malaria seeks three billion dollars
World Bank pledges 37.1 million dollars to combat AIDS in Pakistan
South Africa to offer tourists "AIDS insurance"
Townships hold breath for HIV decision
Bush's aid plan gives hope in Africa's HIV crisis (opinion)
Progress hinders research on AIDS
New AIDS epidemic warning in the Philippines
Drug counseling helps reduce HIV risk
Italian HIV vaccine trial ready to begin
Heart transplant in HIV+ man raises ethics issues
Thompson urges nations to match U.S. commitment to fight AIDS
Australia set for human trials of HIV vaccine
Billions for war on AIDS will go to drug firms, say activists
Kids' risk of HIV after accidental exposure is low
Sex tourism brings rise in AIDS rate
Little action on an AIDS fund
Bad blood between hemophiliacs, Bayer
Chirac trebles AIDS fund but Africa slips down agenda
HIV-1 in eastern Europe
Malariotherapy to treat HIV patients?
Bayer's bad medicine (editorial)
Pumped by AIDS drug
HIV mystery in the Philippines
First HIV vaccine trial to be conducted in the U.S. and Africa
G-8 summit focuses on AIDS, poverty in developing world
HIV sneaks up on Indonesia after Suharto
Australian study finds treatment could stop spread of AIDS in jail
U.K. pledges another £50m to fight AIDS
More news headlines:
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Latest Journal Headlines   [What is this?]
Vaccines:
The association between HCV and HIV-1 in preparatory cohorts for HIV vaccine trials in Thailand. AIDS.
Prevention:
Characteristics of individuals with male-to-male and heterosexually acquired infectious syphilis. Sexually Transmitted Diseases.
Sexual transmission of HIV in Africa. Nature.
Viral infections among HIV-infected and high-risk HIV-uninfected women. Journal of Infectious Diseases.
Advancing HIV prevention: New strategies for a changing epidemic — United States, 2003. Morbidity and Mortality Weekly Report.
Rapid fingerstick testing: A new era in HIV diagnostics. AIDS Clinical Care.
HIV incidence among street youth in Montreal, Canada. AIDS.
The contribution of steady and casual partnerships to the incidence of HIV infection. AIDS.
Public policy regulating private and public space in gay bathhouses. Journal of Acquired Immune Deficiency Syndromes.
Rectal use of nonoxynol-9 among men who have sex with men. AIDS.
Risk factors for incident HIV infection among anonymous HIV testing site clients. Journal of Acquired Immune Deficiency Syndromes.
Incubation and duration of specific symptoms at ARS as independent predictors of progression to AIDS. Journal of Acquired Immune Deficiency Syndromes.
Voluntary HIV testing among inmates. Journal of Acquired Immune Deficiency Syndromes.
Comparison of two strategies for administering nevirapine to prevent perinatal HIV transmission. Journal of Acquired Immune Deficiency Syndromes.
Intensive injection cocaine use as the primary risk factor in the Vancouver HIV-1 epidemic. AIDS.
Is breastfeeding best for HIV-positive mothers?. AIDS.
NeuroAIDS:
Chlamydophila pneumoniae and HIV-associated dementia complex. Journal of Neuroimmunology.
HIV-associated Guillain-Barre syndrome. Journal of the Neurologicals Sciences.
Virology:
B7-H1 is up-regulated in HIV infection and is a novel surrogate marker of disease progression. Blood.
HIV-1 Tat can favor the establishment of neoplasia. Journal of Biological Chemistry.
Inhibition of human immunodeficiency virus type 1 env-mediated fusion by DC-SIGN. Journal of Virology.
Increased in vitro cytopathicity of R5/NSI HIV-1 correlates with a progressive course of infection. Journal of Infectious Diseases.
Decreased stimulation of CD4+ T cell proliferation and IL-2 production by infected dendritic cells. Journal of Immunology.
Review: AIDS pathogenesis: what have two decades of HIV research taught us?. Nature Reviews Immunology.
Natural variation of the nef gene in human immunodeficiency virus type 2 infections in Portugal. Journal of General Virology.
Clade B HIV-1 superinfection with wild-type virus after primary infection. AIDS.
Serum immunoglobulin A (IgA)-mediated immunity in HIV-2 infection. Virology.
The functional relationship between V3 loop and gp120 context with regard to HIV coreceptor usage. Virology.
In-utero transmission of quasispecies among human immunodeficiency virus type 1 genotypes. Virology.
Transmission of HIV-1 infection between trophoblast placental cells and T-cells. Virology.
Heterogeneous clearance rates of long-lived lymphocytes infected with HIV. Proc. Natl. Acad. Sci. USA.
Innate immunity in HIV infection: Effect of viremia on natural killer cell function. Journal of Infectious Diseases.
Microanatomic relationships between CD8+ cells and HIV-1-producing cells in human lymphoid tissue. Journal of Acquired Immune Deficiency Syndromes.
Bystander CD4(+) T lymphocytes survive in HIV-infected human lymphoid tissue. AIDS Research and Human Retroviruses.
Enhanced transcytosis of R5 HIV across tight monolayer of polarized human endometrial cells. Cytokine.
A more accurate assessment of HIV-1 replication dynamics and T-cell decay in vivo. Journal of Virology.
Latent viral reservoir in a SIV-Macaca nemestrina model of HIV-1-infected patients on HAART. Journal of Virology.

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