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August 19, 2008

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——

Vol. 3, No. 7, 18 April 2003

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From Science:
Recruitment of HIV and its receptors to dendritic cell-T cell junctions
Dendritic cell-T cell contact may facilitate transmission of HIV by locally concentrating virus, receptor and coreceptor during the formation of an infectious synapse.

— By Thomas J. Hope et al.

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Hot News:
Broad and potent anti-HIV responses by DNA priming and boosting with protein-adsorbed polylactide coglycolide microparticles
Gag DNA was the most potent technology for CTL induction, while Gag protein adsorbed to PLG microparticles was best for antibody and helper-T-cell responses. These results suggested possible synergy between the DNA and Gag-PLG vaccine technologies for providing strong and broad immune responses. Journal of Virology 77(10), 6087.

From Medscape: U.S. CDC initiative for HIV prevention: An interview with Harold W. Jaffe
How will this program improve recognition and treatment of HIV infection among those who currently do not realize they are infected? (one-time registration required)

From people to places: focusing AIDS prevention efforts where it matters most
Despite the current attention given to controlling the AIDS epidemic in sub-Saharan Africa through treatment, there exists an equally urgent need to improve prevention efforts. AIDS 17(6), 895, 2003

Latest News Headlines [What is this?]
	AIDS: Vietnam's silent sufferers
	U.S. federal spending on HIV prevention to shift course
	Up to 1.5 million Russians have HIV, government says
	OraSure HIV test is centerpiece of national prevention project
	Targeting most likely candidates for staph infections
	Study: Many HIV+ may not take life-saving drugs
	AIDS researchers get warning
	Festival is called syphilis threat
	Sex is the problem — not sloppy medicine
	HIV testing urged in all pregnancies
	ViroLogic shares up on news
	Satellite broadcast: Update on rapid testing for HIV
	GSK urged to change stance on AIDS drugs
	U.K.: Why are sex diseases rising?
	Researcher violated rules, UCLA says
	For lucky few, 'recycled' HIV drugs keep hope alive
	Switzerland concerned over jump in HIV positive rate
	Visionary biotech startup matures into pragmatic industry leader
	Heimlich maneuvers into AIDS therapy
	AIDS activist seeks action in South Africa
	Famine chronic as AIDS devastates continent
	U.K.: Partners stand by HIV patients
	Argentine, Brazilian truck drivers at HIV risk
	U.K.: Survey raises drugs fears
	U.S. HHS awards $1 billion for people with HIV/AIDS
	Roche gets FDA OK for improved HIV test
	Cote D'Ivoire: new grant to fight AIDS epidemic
	HIV-1 subtype linked to transmission in Argentina
	MedMira 3-minute HIV test earns coveted regulatory approval for China
	South Africa: cheaper AIDS drugs to be made locally
	Uganda: appeal for volunteers for HIV/Aids vaccine trials
	The Global Fund seeks experts
	Major gaps in prevention interventions in Latin America
	New AIDS funds bring hope to Haiti
	Red Cross urges governments to help drug addicts and stem HIV/AIDS
	HIV prevention and treatment in South Africa (commentary)
	Fallout from AIDS intensifies starvation threat in Africa
	Oral sex may transmit HIV
	Russia OKs World Bank loan
	Gilead to sell powerful HIV drug to poor nations at steep discount
	Tighter controls set for AIDS drug
	South Africa starts non-invasive AIDS treatment trial
	Panel approves $15 billion for AIDS treatment
	Burma's leaders slowly moving to combat HIV
	Achillion cites progress in AIDS study
	HIV-VAC files patent application for a new HIV vaccine
	U.S. House panel weighs global AIDS effort
	Germany sees first HIV increase since 1997: Report
	Gates Foundation to give $60 million to women's AIDS prevention
	Global AIDS bill hits snag in U.S. Congress
	Class action lawsuit against VaxGen
	Anormed files to test its anti-HIV drug
	The Immune Response Corporation secures $2 million in funding
	AIDS message called a flop
	VaxGen can't add to vaccine proof
	AIDS reaches crisis in Florida, senator says
	Zambia gets $42 million to fight AIDS
	AIDS funds slashed in N.Y.
	Call for review of AIDS vaccine
	HIV risk high in Afghani, Pakistani drug users
	Brazil to build AIDS drugs plants in Africa
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Latest Journal Headlines [What is this?]
Vaccines:
	Susceptibility of mink (Mustera vision)-derived cells to replication by HIV-1. Journal of Virology.
	Evidence for immune-mediated reduction of viral replication in mucosally immunized macaques. Virology.
	Rapid evolution of the neutralizing antibody response to HIV type 1 infection. Proc. Natl. Acad. Sci. USA.
	Broad HIV-specific T cell responses to conserved HIV proteins HEPS women. Journal of Infectious Diseases.
	Vaccine development: Constrained peptide immunogens show improved binding to the anti-HIV-1 gp41 MAb. Biochemistry.
	Dysfunction of CD4 T cell cytokine expression in SHIV/SIV-infected monkeys prevented by vaccination. Journal of Virology.
Prevention:
	Characteristics of individuals with male-to-male and heterosexually acquired infectious syphilis. Sexually Transmitted Diseases.
	Sexual transmission of HIV in Africa. Nature.
	Viral infections among HIV-infected and high-risk HIV-uninfected women. Journal of Infectious Diseases.
	Advancing HIV prevention: New strategies for a changing epidemic — United States, 2003. Morbidity and Mortality Weekly Report.
	Rapid fingerstick testing: A new era in HIV diagnostics. AIDS Clinical Care.
	HIV incidence among street youth in Montreal, Canada. AIDS.
	The contribution of steady and casual partnerships to the incidence of HIV infection. AIDS.
	Public policy regulating private and public space in gay bathhouses. Journal of Acquired Immune Deficiency Syndromes.
	Rectal use of nonoxynol-9 among men who have sex with men. AIDS.
	Risk factors for incident HIV infection among anonymous HIV testing site clients. Journal of Acquired Immune Deficiency Syndromes.
	Incubation and duration of specific symptoms at ARS as independent predictors of progression to AIDS. Journal of Acquired Immune Deficiency Syndromes.
	Voluntary HIV testing among inmates. Journal of Acquired Immune Deficiency Syndromes.
	Comparison of two strategies for administering nevirapine to prevent perinatal HIV transmission. Journal of Acquired Immune Deficiency Syndromes.
	Intensive injection cocaine use as the primary risk factor in the Vancouver HIV-1 epidemic. AIDS.
	Is breastfeeding best for HIV-positive mothers?. AIDS.
NeuroAIDS:
	Chlamydophila pneumoniae and HIV-associated dementia complex. Journal of Neuroimmunology.
	HIV-associated Guillain-Barre syndrome. Journal of the Neurologicals Sciences.
Virology:
	B7-H1 is up-regulated in HIV infection and is a novel surrogate marker of disease progression. Blood.
	HIV-1 Tat can favor the establishment of neoplasia. Journal of Biological Chemistry.
	Inhibition of human immunodeficiency virus type 1 env-mediated fusion by DC-SIGN. Journal of Virology.
	Increased in vitro cytopathicity of R5/NSI HIV-1 correlates with a progressive course of infection. Journal of Infectious Diseases.
	Decreased stimulation of CD4+ T cell proliferation and IL-2 production by infected dendritic cells. Journal of Immunology.
	Review: AIDS pathogenesis: what have two decades of HIV research taught us?. Nature Reviews Immunology.
	Natural variation of the nef gene in human immunodeficiency virus type 2 infections in Portugal. Journal of General Virology.
	Clade B HIV-1 superinfection with wild-type virus after primary infection. AIDS.
	Serum immunoglobulin A (IgA)-mediated immunity in HIV-2 infection. Virology.
	The functional relationship between V3 loop and gp120 context with regard to HIV coreceptor usage. Virology.
	In-utero transmission of quasispecies among human immunodeficiency virus type 1 genotypes. Virology.
	Transmission of HIV-1 infection between trophoblast placental cells and T-cells. Virology.
	Heterogeneous clearance rates of long-lived lymphocytes infected with HIV. Proc. Natl. Acad. Sci. USA.
	Innate immunity in HIV infection: Effect of viremia on natural killer cell function. Journal of Infectious Diseases.
	Microanatomic relationships between CD8+ cells and HIV-1-producing cells in human lymphoid tissue. Journal of Acquired Immune Deficiency Syndromes.
	Bystander CD4(+) T lymphocytes survive in HIV-infected human lymphoid tissue. AIDS Research and Human Retroviruses.
	Enhanced transcytosis of R5 HIV across tight monolayer of polarized human endometrial cells. Cytokine.
	A more accurate assessment of HIV-1 replication dynamics and T-cell decay in vivo. Journal of Virology.
	Latent viral reservoir in a SIV-Macaca nemestrina model of HIV-1-infected patients on HAART. Journal of Virology.
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