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Vol. 2, No. 25, 20 December 2002
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Other Issues:
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This Week's Researchers [What is this?]
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From Science:
MICROBICIDES:
Raising new barriers against HIV infection. A field that suffered a major clinical setback 2 years ago is gearing up for expanded fundraising and product development.
by Rebecca Spieler Trager.
[Free full text article] [About AIDScience articles] [See recent AIDScience articles]
[dEbates: Submit a response to this article]
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Coming Soon:
AIDScience Report:
Current HIV/AIDS-related knowledge, attitudes, and practices among the general population in China: Implications for action. Relatively little is known about the AIDS epidemic in China. Results from a recent survey indicate that the general population is very often uninformed about basic issues, and suggest the need for widespread HIV prevention measures.
by Deborah Holtzman et al.
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Hot News:
Suppression of chemokine receptor expression by RNA interference. Spanish researchers report that suppression of chemokine receptor gene expression by RNA interference (RNAi) can block HIV-1 replication.
AIDS 16(18), 2383, 6 December 2002 [Read abstract]
Related article:
Medscape commentary [Read article] (free one-time registration required).
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U.S. FDA fast-tracks reviews of HIV/AIDS vaccine. VaxGen, Inc. announced this week that the U.S. Food and Drug Administration (FDA) has designated HIV/AIDS vaccine candidates, AIDSVAX B/B and AIDSVAX B/E (rgp120), Fast Track Products. The Fast Track designation will enable rapid regulatory review of AIDSVAX.
[Read press release]
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Latest News Headlines:
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South Africa party vows shift to fight AIDS. Boston Globe. December 20, 2002
| AIDS group asks court to stop AZT patent defense. Yahoo! News. December 20, 2002
| AIDS 'may overturn response to famine'. Financial Times. December 20, 2002
| CDC fact sheet not promoting condom use. New York Times. December 19, 2002
| New AIDS drug likely to fall short of 2003 demand. Yahoo! News. December 19, 2002
| The Immune Response Corporation granted patent in South Africa. Immune Response release. December 19, 2002
| Cruel epidemic hits kids hard — nearly 300,000 orphaned. San Francisco Chronicle. December 19, 2002
| Thailand overwhelmed by runaway AIDS. San Francisco Chronicle. December 19, 2002
| World Bank gives US$12.6 million to Sri Lanka to stop spread of AIDS. Yahoo! News. December 18, 2002
| FDA news boosts VaxGen shares 21%. Los Angeles Times. December 17, 2002
| U.S. to reject accord on access to cheap medicines. Financial Times. December 17, 2002
| Gilead to provide Viread in 68 developing countries at no profit. Gilead release. December 17, 2002
| Researchers find part of AIDS virus can hide itself. Nando Times. December 17, 2002
| Companies agree to continue HIV drug safety studies. Yahoo! News. December 17, 2002
| More than words to fight AIDS (opinion). New York Times. December 16, 2002
| VaxGen receives fast track designation from FDA for AIDSVAX B/B and AIDSVAX B/E. VaxGen release. December 16, 2002
| HIV infection rate among South African children found to be 5.6%. BMJ News. December 16, 2002
| India announces plan to inform HIV infected blood donors. BMJ News. December 16, 2002
| HIV spotted inside human cell. BBC News. December 15, 2002
| Students sell their bodies for a quick buck. Bangkok Post. December 15, 2002
| VaxGen falls 22 percent after 'Nature' story. New York Times. December 14, 2002
| Drive to increase HIV drug access. BBC News. December 13, 2002
| HIV infection rates could be cut right across Africa, study shows. The Independent. December 13, 2002
| WTO meeting on affordable drugs suspended. Nando Times. December 13, 2002
| South Africa's AIDS fallout may force government to act. San Francisco Chronicle. December 13, 2002
| U.S. FDA grants clearance for Celera Diagnostics’ ViroSeq HIV-1 genotyping system. Celera release. December 12, 2002
| New insights into elusiveness of AIDS virus. Yahoo! News. December 12, 2002
| U.S. establishes health agreement with Ethiopia. HHS release. December 12, 2002
| Research offers new insights into spread of HIV/AIDS in South Africa. Business Day. December 11, 2002
| Applied Bio, Celera to market HIV gene system. Yahoo! News. December 11, 2002
| Transgene signs vaccine manufacturing agreement with IAVI. Transgene release. December 11, 2002
| Canada panel pushes 'safe' drug injection sites. Reuters Health. December 11, 2002
| Immune Response announces completion of private offering of $8.4 million. Immune Response release. December 11, 2002
| Time to act: global apathy towards HIV/AIDS is a crime against humanity. Lancet commentary. December 11, 2002
| Access to antiretroviral drugs in Brazil . Lancet. December 11, 2002
| Teenage African women and HIV-1 infection. Lancet. December 11, 2002
| France steps up pressure for cheap drug deal. Financial Times. December 10, 2002
| Official: Zambia needs $270 million to tackle AIDS. Yahoo! News. December 10, 2002
| Outdated contraceptive may help in Third World. San Jose Mercury News. December 10, 2002
| West's response to AIDS inadequate. Newsday. December 9, 2002
| Brisbane firm's clinical trials of AIDS vaccine nears completion. San Francisco Chronicle. December 9, 2002
| Thai AIDS pill raises hopes of poor, concern of skeptics. Boston Globe. December 8, 2002
| UK: NHS staff 'face HIV tests'. BBC News. December 8, 2002
| The AIDS crisis and human rights (opinion). Boston Globe. December 8, 2002
| Massachusetts: Court announces needle exchange ruling. Newsday. December 8, 2002
| Botswana giving fight of its life. Philadelphia Inquirer. December 8, 2002
| The HIV vaccine that no one wants (opinion). Washington Times. December 8, 2002
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More news headlines: This week | Last week | Search archive |
Latest Journal Headlines:
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| HIV-1 evades antibody-mediated neutralization. Nature. (Posted: December 17, 2002) | | HIV prevalence among foreign- and US-born clients of public STD clinics. American Journal of Public Health. (Posted: December 17, 2002) | | NeuroAIDS: A randomized clinical trial of CPI-1189 for HIV-associated cognitive-motor impairment. Neurology. (Posted: December 17, 2002) | | Comparison between HIV- and CMV-specific T cell responses in long-term HIV infected donors. Clinical and Experimental Immunology. (Posted: December 17, 2002) | | Short-course therapy with zidovudine plus lamivudine for prevention of mother-to-child transmission. Clinical Infectious Diseases. (Posted: December 17, 2002) | | Allocating HIV-prevention resources: Balancing efficiency and equity. American Journal of Public Health. (Posted: December 17, 2002) | | Screening for HIV infection in high-risk communities by urine antibody testing. Journal of Acquired Immune Deficiency Syndromes. (Posted: December 17, 2002) | | Recombinant multi-epitope vaccine induced predefined epitope-specific antibodies against HIV-1. Immunology Letters. (Posted: December 17, 2002) | | NeuroAIDS: Neurocognitive dysfunction predicts postmortem findings of HIV encephalitis. Neurology. (Posted: December 17, 2002) | | NeuroAIDS: Up-regulation of MAP2e-expressing oligodendrocytes in the white matter in HIV-1 encephalitis. Neuropathology and Aplied Neurobiology. (Posted: December 17, 2002) | | NeuroAIDS: Neurotoxic effects of Tat require function of a polyamine sensitive-site on the NMDAr. Brain Research. (Posted: December 17, 2002) | | NeuroAIDS: Neuroanatomical distribution of CXCR4 in adult rat brain. European Journal of Neuroscience. (Posted: December 11, 2002) | | Subcompartmentalization of HIV-1 quasispecies in distinct genital tissues. AIDS Research and Human Retroviruses. (Posted: December 11, 2002) | | A 13-week subchronic intravaginal toxicity study of the novel anti-HIV and spermicidal agent PHI-346. Toxicologic Pathology. (Posted: December 11, 2002) | | Restricted replication of primary HIV-1 isolates using both CCR5 and CXCR4 in Th2. Journal of Leukocyte Biology. (Posted: December 11, 2002) | | Blood banking in China. Lancet. (Posted: December 11, 2002) | | Multiple determinants are involved in HIV coreceptor use. Journal of Leukocyte Biology. (Posted: December 11, 2002) | | Prevention of HIV-1 infection in human PBMCs by specific RNA interference. Nucleic Acids Research. (Posted: December 11, 2002) | | HIV-1 subtype C exhibits higher transactivation activity of Tat than subtypes B and E. Microbiology and Immunology. (Posted: December 11, 2002) | | Double-stranded nef RNA interferes with human immunodeficiency virus type 1 replication. Microbiology and Immunology. (Posted: December 11, 2002) | | NeuroAIDS: Mechanisms of HIV type 1-induced cognitive impairment. AIDS Research and Human Retroviruses. (Posted: December 8, 2002) | | A sensitive and specific enzyme-based assay detecting HIV-1 virion fusion in primary T lymphocytes. Nature Biotechnology. (Posted: December 8, 2002) | | Mamu-A*01 allele-mediated attenuation of disease progression in SHIV infection. Journal of Virology. (Posted: December 8, 2002) | | Elevated levels of circulating interleukin-18 in HIV-infected individuals. Journal of Virology. (Posted: December 8, 2002) | | HIV-1-specific CD8+-T-cell responses for groups of individuals with different HLA-B*35 genotypes. Journal of Virology. (Posted: December 8, 2002) | | Neutralizing antibody induced in mice by novel glycoconjugates of HIV-1 gp120 and env2-3. The Journal of Infectious Diseases. (Posted: December 8, 2002) | | Interleukin-18 enhances HIV-1 production in a human chronically-infected T cell line (H9-V). Cell Biochemistry and Function. (Posted: December 8, 2002) | | Short constrained peptides that inhibit HIV-1 entry. Proc. Natl. Acad. Sci. USA. (Posted: December 8, 2002) | | Vaccination with apoptotic HIV-1/murine leukemia virus-infected cells. Journal of Immunology. (Posted: December 8, 2002) | | NeuroAIDS: Abnormal brain activation on functional MRI in cognitively asymptomatic HIV patients. Neurology. (Posted: December 8, 2002) | | RNA interference directed against viral and cellular targets inhibits HIV-1 replication. Journal of Virology. (Posted: December 8, 2002) |
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