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AIDScience Perspective:
AIDS vaccines and HIV transmission via breastfeeding. Is there a role for vaccines in protecting infants against HIV in breast milk?
By Emily Bass
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Hot News:
Virologic and immunologic determinants of heterosexual transmission of HIV-1 in Africa. Something about the biology of HIV-positive women makes them much more contagious than the level of virus in their blood would indicate. The results of this study suggest gender-specific differences in the biology of heterosexual transmission.
AIDS Research and Human Retroviruses 17(10):901-910
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Effects of CCR5-delta32, CCR2-64I, and SDF-1 3'A alleles on HIV-1 disease progression. In this latest study on gene variations affecting HIV disease progression, it was found that two of the alleles—CCR5-delta32 and CCR2-64I—appear to significantly slow HIV patients' progression to AIDS.
Annals of Internal Medicine 135(9):782-795
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Protection of rhesus macaques against disease progression from pathogenic SHIV-89.6PD by vaccination with phage-displayed HIV-1 epitopes. New vaccine approach may help overcome the antigenic polymorphism of HIV-1.
Nature Medicine 7:1225-1231
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Determinants of HIV-1 shedding in the genital tract of women. Results from this study indicate that HIV-1 shedding in infected women (and therefore transmission risk to a sexual partner) is possible even when blood levels of HIV are low.
Lancet 358(9293):1593-1601, November 10, 2001
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Guidelines for laboratory test result reporting of HIV-1 viral load determination. Recommendations from a CDC Working Group.
MMWR 50(RR20):1-12, November 16, 2001
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Revised guidelines for HIV counseling, testing, and referral. Technical expert panel review of Centers for Disease Control (CDC) HIV counseling, testing, and referral guidelines (replace CDC's 1994 guidelines).
MMWR 50(RR19):1-58, November 9, 2001
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From Medscape: HIV/AIDS annual update 2001. Now complete—a collection of 11 clinical reviews, authored by leading authorities.
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